All male patients experiencing new breast symptoms including a palpable lump, breast pain, tenderness, or swelling, should seek consultation with a primary care physician and be referred for diagnostic imaging . During infancy, puberty, and in middle-aged to older men, gynecomastia can be common.Gynecomastia must be distinguished from pseudogynecomastia or lipomastia, which refers to the presence of fat deposits in the breast area of obese men. Tender and sensitive breasts and/or nipples. Some antibiotics. In order to properly diagnose the etiology of the gynecomastia, the clinician must understand the hormonal factors involved in breast development. Gynexin is by far the most popular. Many of the medications associated . A. Drugs cause about 10-25 % of cases. Antiandrogens, protease inhibitors, and nucleoside reverse transcriptase inhibitors are the mos … If you have enlarged breasts because of fat . It can happen to newborn babies, teenage boys going through puberty, and grown men as they age. It is not entirely clear why t. highly active anti-retroviral therapy (HAART) for HIV disease. Efavirenz (Sustiva) is an HIV medicine that is more associated with gynecomastia than other medications. Below is a list of common medications used to treat or reduce the symptoms of gynecomastia. Gynecomastia usually resolves without any treatment, but if there is an underlying condition, it may need treatment. Gynecomastia is a condition that causes a swelling of the breast tissue in men. All these factors seem different; they are root for producing excess estrogen that causes male breast. Gynecomastia is enlargement of the glandular tissue of the male breast. Gynecomastia in adults. Medications. Researchers have estimated that the prevalence among men ages 50 to 80 is between 24% and 65%. As a number of factors can alter the estrogen:androgen ratio, several pathophysiologic mechanisms are associated with drugs causing this disorder. Certain classes of medications pose a higher risk than others. Some of the medicines used to treat heartburn can also trigger the gynecomastia, as can some drugs used . Click on the drug to find more information including the brand names,dose,side-effects, adverse events, when to take the drug . If you have gynecomastia or are concerned about developing it, talk to your healthcare provider for guidance. Gynecomastia can also be caused by medications that alter . Poor diet. However, there is a risk of hyperkalemia . Am on adderall for energy and to clear my brain fog. An imbalance in hormones, with a relative excess of estrogens compared with androgens (male hormones), causes gynecomastia. Tuerk M. Plastic and Reconstructive Surgery, 01 Dec 1993, 92(7): 1411 PMID: 8248425 . Many drugs can cause gynecomastia (see Table 1) as much as several active principles, which have been associated to this condition. [symptoma.com] Loss of sexual desire and drive, lack of sexual fantasies, gynecomastia (enlargement of breasts), and diminished facial hair suggest low testosterone levels. Drugs used to treat prostate cancer, or an enlarged prostate are a common cause of the condition. 3 The active principles known for most frequently causing gynecomastia are exogenous oestrogens, anti-androgens, 5 alpha-reductase inhibitors, spironolactone and cimetidine. This list of drugs that cause gynecomastia was originally on Michael Bermant, MD's web page. Gynecomastia can also be pathological, arising with obesity, steroid use, pharmacologic agents, medical conditions including chronic liver and renal failure or hypogonadism. Digitalis used to treat congestive heart failure. Specifically, medications that cause gynecomastia or enlarged male breasts include: Psychoactive drugs, including antidepressants and anti-anxiety medications. Finasteride, which is FDA approved for treating male balding at a dose of 1 mg daily, is a medication . Increased facial hair is a documented side effect of Rogaine. In short, Gynecomastia is caused by an imbalance or hormones. Swelling of the breast gland and/or nipples. Street drugs like amphetamines, marijuana, heroin, methadone, and even alcohol can cause gynecomastia. While it may work to reduce that type of fat, it does not address the underlying cause - glandular breast . Nuttall FQ, Warrier RS, Gannon MC. Also, a relatively lengthy list of medications can induce gynecomastia. Typically, it's caused by an imbalance of the hormones testosterone and estrogen. Some work to inhibit estrogen production in men, stopping the tissue production in male breasts that causes the protruding "man boob" appearance, and some work on overall fat reduction. Finasteride-Induced Gynecomastia: Myths and Misconceptions. While gynecomastia is a known side effect of Propecia, it is not associated with minoxidil use. Antibiotics. Both reversible and irreversible gynecomastia have been experienced with a wide range of psychiatric drugs, including reuptake inhibitor antidepressants like SSRIs and SNRIs (as well as other kinds of antidepressants). Hormone-secreting tumors. A number of antibiotics--although by no means all--can cause gynecomastia. References. It is asymptomatic but some patients have reported pain and discomfort in the breast(s). Gynecomastia can be normal in newborn babies due to exposure . In the case of enlarged breasts caused by fat deposits, you have a different condition known as pseudogynecomastia.". Drug-induced gynecomastia is common and might account for a quarter of all cases, including those among children. 4) Development of male breast through the consumption of drugs and alcohol. Examples of conditions that can cause gynecomastia include cirrhosis of the liver, low testosterone, obesity, chronic . Known drugs that can cause gynecomastia. The risks are generally very . Congenital Disorder. But when searching for a list of drugs that cause gynecomastia (which I am recently noticing a small amount of) its on the list, well . Many medications may cause gynecomastia. There are other factors too that can disrupt the hormonal balance in men. These are as follows-Age- Age is a crucial factor for risk of gynecomastia. Recreational drugs, such as alcohol and marijuana. Hypoandrogenism. They . Finally, street drugs (including marijuana, amphetamines, heroin, and methadone) and alcohol may cause gynecomastia. Gynecomastia (American English) or Gynaecomastia (British English) is the development of abnormally large breasts on men. There are several medications that, when taken on a regular basis for long periods of time, may lead to the development of gynecomastia. Gynecomastia in adults. The condition called gynecomastia causes men and boys to develop enlarged breast tissue. According the the web page, he is a board certified plastic surgeon. Gynecomastia is defined as benign proliferation of glandular breast tissue in men. Medications. Drugs.com provides accurate and independent information on more than 24,000 prescription drugs, over-the-counter medicines and natural products. Gynecomastia can also happen due to certain side effects of medications, and the list includes: A diuretic, named "spironolactone (Aldactone)", which . Medications. Enlargement is usually transient, bilateral, smooth, firm, and symmetrically distributed under the areola; breasts may be tender. These drugs (according to the Physician Desk Reference) can cause gynecomastia as a side effect. Gynecomastia may be abnormal as, for example, in Klinefelter's syndrome. It can be caused by a natural decrease in testosterone or increase in estrogen. The diagnosis is primarily clinical. Gynecomastia in adults. It is the world's most widely consumed psychoactive drug. Gynecomastia and drugs: a critical evaluation of the literature. Gynecomastia is a common finding in males, with an incidence that varies widely globally. 2) Development of gynecomastia through use of steroids neglecting PCT (Post Cycle Therapy) 3) Use of several prescribed medication and steroid can cause gyno. Lipomastia has different causes and symptoms, so it needs to be treated differently. Share this article Share with email . Unfortunately, there are a few types of medications out there that can also cause gynecomastia to occur. Cardiovascular drugs, such as captopril and digitoxin. Sexual Dysfunction. Other drugs such as bupropion hydrochloride, mirtazepine (remeron) and nefazodone seldomly cause ED or FSD. Other rare causes of gynecomastia include exposure to phthalates and lead, emotional stress, and repetitive mechanical stress causing unilateral symptoms . These lawsuits accuse the company of releasing a defective drug into the marketplace and failing to provide adequate warnings for the dangerous side effects associated with . List of drugs used to treat the medical condition called Gynecomastia. Gynecomastia is a benign condition. There are many other drugs that can cause abnormal breast growth in men, such as: Anti-anxiety medications, such as diazepam (Valium) Some antibiotics. Physiologic gynecomastia is common in newborns, adolescents, and older men. Researchers have estimated that the prevalence among men ages 50 to 80 is between 24% and 65%. Class II medications (medications implicated in more than 10 cases of acute pancreatitis): rifampin, lamivudine, octreotide, carbamazepine, acetaminophen, phenformin, interferon alfa-2b, enalapril, hydrochlorothiazide, cisplatin, erythromycin, and cyclopenthiazide. Psychoactive agents, such as diazepam and tricyclic antidepressants. Some anti-androgen medications can cause gynecomastia, as these drugs are usually used to treat prostate enlargements and prostate cancer. Its causes range from benign physiological processes to rare neoplasms. However, most men with the condition experience no symptoms. The condition can occur physiologically in neonates, in adolescents, and in the elderly. A number of medications can cause gynecomastia. As many men are unaware of the condition, yet its cause and name, they don't know the solution. It is essentially a fat burner that specifically targets the adipose tissue (fat) in men's breasts. This . Commonly known as "man boobs", gynecomastia is often caused by changes in hormone levels and can be resolved with surgical techniques. Treatment. Further, it could be a result of a congenital disorder or could also be caused from a number of other reasons such as alcoholism, chest wall trauma, cystic fibrosis, herpes zoster infection, HIV, Myotonic . Heart medications, including alpha-blockers and ACE inhibitors. Types of medications that can cause gynecomastia: Drugs of abuse like heroin, alcohol, marijuana, and opioids; Anti-androgen medications are mainly used to treat prostate cancer when used for men. Answer (1 of 3): We don't know, and sometimes. Common known causes of gynecomastia include physiological hormonal changes, use of medications and pathologica l entities such as cirrhosis , hyperthyroidism , testicular tumors and hypogonadism. True gynecomastia results from growth of the glandular, or breast tissue, which is . Less common causes include androgen insensitivity syndrome , Kallmann syndrome, defects of testosterone pathway and tumors. In 10-25% of cases, it is caused by drugs. But dozens of other medications may also trigger this reaction. Enlarged breasts in boys and men often improve without treatment. As males reach puberty, they are prone to developing gynecomastia due to hormonal changes. Definition of Gynecomastia. Gynecomastia can cause significant psychological distress or unease. Drugs That Can Cause of Gynecomastia. Researchers have estimated that the prevalence among men ages 50 to 80 is between 24% and 65%. However, for some reason, the web site is completely gone. Certain medications and diseases can also cause male breast tissue to swell and get bigger. Anything that disrupts the balance of estrogen and testosterone in the body may lead to an increase in breast tissue (called gynecomastia in men). Pubertal gynecomastia that persists into adulthood is responsible for another 25 % of cases. Parallel to female breast development, estrogen, GH, and IGF-1 are required for breast growth in males. Because potassium-sparing diuretics do not promote the secretion of potassium during diuresis they do not cause hypokalemia (low potassium levels). [ 32] Up to 80% of patients report partial to complete . Gynecomastia is often due to an imbalance of testosterone and estrogen hormones. For a full list of implicated drugs, click here. 7 The drugs that can cause gynecomastia are listed in Table 1. This may occur if two hormones in your body are thrown out of balance. It . Medications. Less common side effects are low blood pressure, abnormal heart rhythm and dizziness. The causes is generally unknown in about 25 % of cases as well. Gynecomastia is a relatively common disorder. Although many medications can cause this complication, it is not generally recognized as a side effect of statin-type cholesterol . Anti-ulcer drugs (such as Zantac, Tagamet, and Prilosec); Anti-androgen or estrogen therapies for prostate cancer; Gynecomastia is a benign male breast enlargement. Hyperthyroidism. Tricyclic antidepressants. First and foremost, you should look into whether the medications you're taking can cause gynecomastia. AIDS medications. An abundance of estrogen . Lactation of the nipples. Gynecomastia can also be a result of tumors, systemic, including Adrenal, Cirrhosis, renal failure, or Thyrotoxicosis. Some of the drugs that have shown possible connection to gynecomastia are: Anabolic steroids. Recreational or illegal drugs like alcohol, marijuana and methamphetamines can also cause gynecomastia. A: Male breast enlargement goes by the medical term gynecomastia. HIV-positive men sometimes receive a treatment regimen called highly active antiretroviral therapy, which can cause gynecomastia. Gynecomastia (also spelled gynaecomastia) is the abnormal non-cancerous enlargement of one or both breasts in males due to the growth of breast tissue as a result of a hormone imbalance between estrogen and androgen. Male breast enlargement goes by the medical term gynecomastia. In adolescent boys, 90% of such cases the symptoms disappear in a matter of months to a few years at most. . Physiologic gynecomastia that develops during puberty usually resolves within about 6 . Drugs for the Treatment of Gynecomastia: ACE inhibitor drugs for hypertension. Drugs account for about 20% of gynecomastia cases in men. Certain medications can also cause gynecomastia. Drugs that Cause Gynecomastia Recommended by Dr. Michael White, Updated on October 25th, 2018 Gynecomastia is the development of breasts in males. Below is a list of common medications used to treat or reduce the symptoms of gynecomastia. Certain medications and medical conditions can also lead to the development of gynecomastia in males. It can happen when the balance of two hormones in your body is thrown off. More germane to our topic is a less well-known cause--a side effect of certain drugs. Although many medications can cause this complication, it is not generally recognized as a side effect of statin-type cholesterol-lowering drugs. These include antipsychotics, proton pump inhibitors, and hormones such as testosterone. In all of these different causes there is an underlying hormonal issue - typically an increase in the estradiol/testosterone ratio. There are a few classes of medications that can cause gynecomastia, which is enlargement of breast tissue in men. What is gynecomastia is a question frequently asked. Other drugs including cimetidine, ranitidine, and proton pump inhibitors can cause Gynecomastia via a mechanism distinct from that of chemotherapeutic agents [9, 19]. The list of drugs that cause gynecomastia in the Merck Manual is over fifty long . If the condition is due to one drug, the patient may need to switch to another drug. Some patients seek an early evaluation . Other common side effects are scalp irritation, itching and redness. Ulcer medications, such as cimetidine (Tagamet) A. Medications that cause gynecomastia. Medications That Cause Gynecomastia. —-David (TakingThePlunge) Temporary enlargement of the breasts is not unusual or abnormal in boys during adolescence or during recovery from malnutrition. Gynecomastia is a condition that makes breast tissue swell in boys and men. These include: Anti-androgens used to treat an enlarged prostate, prostate cancer and other conditions. A number of medications can cause gynecomastia. Look up any medications you are taking to see if they could be causing your problem, and then discuss it with your doctor. According to Stanford Healthcare, gynecomastia can also be caused by common medications, such as: Steroids, such as prednisone or dexamethasone. Gynecomastia treatment drugs, both prescription and OTC, work in different ways. However, most men with the condition experience no symptoms. Other Drugs that Cause Gynecomastia. Several gynecomastia pills are currently on the market, including Gynexin, Gynectrol and GyneMax. Patients being treated with . During infancy and puberty, enlargement of the male breast is normal (physiologic gynecomastia). Question. Gynecomastia is a condition that involves enlargement or overdevelopment of breast tissue in men and boys. Mass Tort. Researchers have estimated that the prevalence among men ages 50 to 80 is between 24% and 65%. Below is a list of the most common category of medications that have been linked to gynecomastia. Follow the links to read common uses, side effects, dosage details and read user reviews for the drugs . Alcohol and drugs can cause gynecomastia by mimicking estrogen and stimulating androgen production. Causes of Gynecomastia Other Than Drugs. [medicinenet.com] However, most men with the condition experience no symptoms. This is, by no means, an exhaustive list and the effects of medications will impact each person differently. Since a balance exists . Diuretics. Medications. Recreational drugs, including marijuana and heroin. Class III medications (all medications reported to be associated with pancreatitis). These include: Anti-androgens used to treat an enlarged prostate, prostate cancer and other conditions. Its pathophysiologic mechanism includes exposure to exogenous . The term comes from the Greek gyne meaning "woman" and mastos meaning "breast". List of drugs associated with a side effect named as Gynecomastia or Breast Enlargement In Male and related drug information. This includes spironolactone, some antipsychotics, and certain prostate cancer medications. A long list of medications can cause gynecomastia. But the list of potential causes is long and a full review is needed for anyone with concerns about gynecomastia. San Jose, California-It is important to try to determine the cause of gynecomastia in order to avoid its re-occurrence There are some cases where the cause will remain unknown, but for some, doctors will look at the types of medication or drugs, both prescription and over-the-counter, legal and illegal for a possible connection to the development of the . Lawsuits have been filed against Janssen Pharmaceuticals alleging that Invega can increase a user's risk of developing gynecomastia and/or hyperprolactinemia. Medications used to treat breast cancer and other conditions may be helpful for some men with gynecomastia. Gynecomastia in adolescents often goes away without treatment in less than two years. Calcium channel blockers used to treat hypertension. 6 Although the mechanisms by which many medications induce gynecomastia are not yet understood, some mechanisms are clear. Penicillamine. An increased diameter of the nipple. Tamoxifen, an estrogen antagonist, is effective for recent-onset and tender gynecomastia when used in doses of 10-20 mg twice daily. Medication-induced gynecomastia may account for as much as 20% to 25% of the incidences (Benbo & Carlson 2004). 28. Propecia for hair loss and Proscar for prostate (both finasteride) can trigger the problem, because they work by blocking an enzyme responsible for converting testosterone to DHT. Caffeine: Caffeine is a central nervous system stimulant of the methylxanthine class. These include: Anti-androgens used to treat an enlarged prostate, prostate cancer and other conditions. Medicines used to treat ulcers, such as cimetidine (Tagamet HB) Medicines are used to treat epilepsy, such as (Dilantin). A number of medications can cause gynecomastia. Gynecomastia: Excessive development of the male breasts. Diagnosis. Gynecomastia in adults. Examples of Beta-2 stimulators that raise blood sugar include: Proventil, Alupent, Serevent, Foradil, Brethine and Theo-Dur. If the patient is using the drug for a short time, the condition will be temporary. If this condition makes you self-conscious, you may consider breast reduction surgery. ing estrogens, causing gynecomastia. Steroids, including prednisone or dexamethasone. Gynecomastia is a condition where men develop breasts. Treatment may be necessary if gynecomastia doesn't improve on its own or if it causes significant pain, tenderness or embarrassment. Since it can cause a certain amount of embarrassment, discomfort, and anxiety, patients may seek diagnostic evaluation and treatment. Breast enlargement is associated with estrogen hormones, whether taken as birth control pills or in postmenopausal therapy. 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